The U.S. Chamber of Commerce agrees with the spirit of the European Union’s (“EU”) Corporate Sustainability Due Diligence (“CS3D”) Directive (“Directive”), which seeks to improve the efficiency,resilience, and long-term sustainability of global supply chains. The Chamber is concerned, however, about the misalignment between the CS3D’s goals and potential requirements, and what business can practically accomplish. Legal certainty and proportionality should be key tenets of any regulatory approach regarding due diligence.